Posted in Corrective Exercise, Ketogenic Life, Of Heart and Mind

Colder Temperatures Positively Affect Your Metabolism

Have you ever heard of BAT? Brown adipose tissue?

There exists two forms of fat in the human body: white fat and brown fat. The Scientific American shares that white fat cells store energy in the form of a single large, oily droplet that is otherwise relatively immobile. On the other hand, brown fat cells contain many smaller droplets, as well as energy machines known as mitochondria. Only in recent years have researchers found ways to convert white fat to brown fat. Having more active brown fat present can improve insulin sensitivity to help banish type 2 diabetes and heighten the body’s metabolism to reduce body weight.

Amongst multiple research studies, it is unanimous that lower temperatures force the body to induce thermogenesis, the heat generation that increases your body’s core temperature in order to bring it to homeostasis. When this takes place, white fat can then act like brown fat, otherwise called “beige” fat.

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Luckily, these temperatures do not have to be low enough to cause muscle quivering. In 2013, Japanese researchers had 12 young men with lower than average brown fat amounts to sit in a 63 degree Fairenheit room for two hours a day for six weeks. After six weeks, those 12 men were burning an extra 289 calories and PET-CT scans verified the heightened quantity of brown fat cells. They believe that exposure to these colder temperatures over six weeks increased the activity of a gene named UCP1, which seems to guide the conversion of white fat into beige fat. They also understand that exercise helps to increase UCP1 in conjunction with a hormone called irisin that helps convert white fat to beige fat.

A study supported by the National Institute of Health (NIH) in 2014 had 5 healthy men reside in a clinical research unit for 4 months. They would do their normal daily activities during get day then return to their private room for at least 10 hours each night. The temperature of the room was set to 24 °C (75 °F) during the first month, 19 °C (66 °F) the second month, 24 °C again for the third month, and 27 °C (81 °F) the fourth and last month. Each month, the men underwent extensive evaluation, including energy expenditure testing, muscle and fat biopsies, and PET/CT scanning of an area of the neck and upper back region to measure brown fat volume and activity.

After a month of exposure to 19 °C (66 °F), the participants showed a 42% increase in brown fat volume and a 10% increase in fat metabolic activity. During the following month of neutral temperature, these alterations returned to near baseline, and then completely reversed during the month of exposure to 27 °C (81 °F). All the changes occurred independently of seasonal changes.The increase in brown fat following cold exposure was accompanied by improved insulin sensitivity after a meal during which volunteers were exposed to mild cold. The extended exposure to mild cold also resulted in significant changes in metabolic hormones such as leptin and adiponectin.

Yu Hua Tseng, Ph.D., the Principal Investigator in the Section on Integrative Physiology and Metabolism at Joslin Diabetes Center, says that “brown fat is a natural defense system for obesity, diabetes and related diseases or conditions.” Because of the supporting research, the idea of activating brown fat as a way to combust this excess energy is now an attractive area of research for developing new treatments to help combat obesity and various metabolic diseases. Increasing your metabolic baseline by activating brown fat could be the key to combating such diseases or conditions.

Imagine this: exercise while being exposed to colder temperatures. George King, M.D., Chief Scientific Officer at Joslin Diabetes Center, recommend combining these known brown-fat activators by working out in the cold to get the maximum benefit. By doing so, you’d be revving up your conversion of white to beige fat, in turn burning more calories and improving insulin sensitivity!

Season’s Greetings,

Coral A.J. Gibson

Posted in Ketogenic Life

Exogenous vs. Endogenous Ketones

The empirical research and powerful testimonials concerning ketosis are of abundance.

You might have had this question run across your mind, like many people looking for health optimization: what is the difference between taking exogenous ketones and following a ketogenic diet?

Either way, the body will benefit. Let’s talk about this difference.

Simply put, “exogenous” refers to something that is sourced from outside of the body. All supplements are therefore considered exogenous because they are ingested rather than created by the body. “Endogenous” refers to something created within the body.

Is that simplified enough? I hope so.

Now the question becomes what are the implications of that exogenous vs. endogenous? Are there any specific differences between taking exogenous ketones and producing endogenous ketones? This video from Michael Rutherford clearly explains the difference; don’t let it be too complicated.

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Alchemy Athletics provides this incredible insight to the community. Endogenous “ketosis can be unsustainable in the long-term considering that just a small amount of carbohydrates or excess protein can kick you out of ketosis.” This is very true. And this is why exogenous ketone use can be so handy in long-term health and wellness. Learn more about the benefits of exogenous ketone supplementation in Alchemy Athletics’ Ketones 101 and read through the resources listed at the bottom of the article!

Onward and Upward,

Coral A.J. Gibson

Posted in Ketogenic Life

Ketones and Sleep

Thank you for your patience! I slacked off on my posts the past couple of weeks. But I’m back and ready to rock and roll!! Today’s topic is SLEEP. I’ve gotten so many clients who have raved about how much sleep has improved upon implementing their exogenous ketones on a daily basis. Rather than taking hours to fall asleep or waking up multiple times a night, they begin experiencing SLEEP!! And if you know anything about sleep, it is the most powerful form of mental and physical recovery and stress relief.

As avid exercisers, the exogenous ketones help repair inflammation in both body and brain tissues more rapidly and effectively!! How incredible is that?!

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If you don’t get sufficient sleep! (General terms)

Sleep is entirely a brain thing. Neuroscience can dig into the concept of sleep in more detail than you could ever imagine. Conditions such as epilepsy, sleep apnea, narcolepsy, TBI, concussions (among others) are 100% controlled by the brain. In providing more fuel to the brain to reduce inflammation and provide circulation of blood and nutrients through the use of exogenous ketones, your brain may be able to heal itself. Once again, you will be able to thoroughly enjoy the beauty sleep we all require. Giving the brain this super jet fuel (as many people have come to call it!) also makes sure the brain does not get depleted of vital nutrients, which may restrict certain parts of the brain unannounced.

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If you don’t get sufficient sleep! (Science jargon)

For today’s post, I would like to share with you some fantastic podcasts and videos that you are able to listen to during a busy day. You can plug it in and listen while you go on a trail walk, or play it on your computer speakers while you clean up the house. Whatever you may be doing, take some time to listen to the abundance of knowledge the following experts bring to the conversation.

This first one is from Tim Ferriss’ podcast as he talks with Dr. Dominic D’Agostino (whom you’ve heard about plenty on my site) and Dr. Peter Attia on the topic of exogenous ketones and jet fuel! http://fourhourworkweek.com/2015/11/03/dominic-dagostino/

On this second site, Dr. D’Agostino’s blog site, he shares a TED Talk he presented discussing the use of the ketogenic diet for patients with epilepsy and cancer. http://ketonutrition.blogspot.com/2014/02/the-charlie-foundation-for-ketogenic.html?view=sidebar

Wishing you a good night’s rest,

Coral J.

cj1005.pruvitnow.com

Posted in Ketogenic Life

Can’t Commit to the Keto Diet Yet?

Do you have a spouse that’s skeptical about you taking their spaghetti and garlic bread out of their weekly meal plan? A child that is in a routine of cereal for breakfast and a PB&J sandwich for lunch? A friend that laughs when you even mention the possibility that carbs can be removed from your diet and have BENEFIT? I’m sure that everyone has some doubt that this “ketogenic” phase will come and go like every other diet fad out there. Even with that skepticism, there’s still a first step that can be taken to increase the function of your body, even if you are currently consuming carbs. Putting your body into a state of ketosis is a MIRACULOUS thing.

A study conducted in 2014 discusses that “ketone metabolism by healthy tissue would likely mitigate some of the adverse side effects of standard of care as ketones have been shown to protect against oxidative stress” (Poff, Ari, Arnold, Seyfried and D’Agostino). This means to say that even though you may not limit your consumption of carbohydrates enough to keep your body in a state of ketosis, the consumption of supplemental exogenous ketones can help keep your body in such a state and still reap the benefits of the ketogenic diet. Triglyceride levels decrease, HDL (good cholesterol) levels increase, insulin resistance decreases and blood pressure decreases. For all of these things to take place without a single medication is ASTOUNDING!

Betahydroxybutyrate is a ketone ester naturally occurring in the body, but is not utilized well in a high-carb low-fat diet. Supplementation of this ketone ester has shown to be “a feasible and efficacious cancer therapy” for mice, and is in the process of being more thoroughly investigated for cancer treatment for humans (Poff et al., 2014). If this ketone ester can rid the body of CANCER, it has a lot more to offer than any other supplement out there. So if your spouse, child, or friend wants to optimize the function of their body, there’s no other way to go. This is it, ladies and gentlemen!

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Pruvit’s KETO//OS is the “first of its kind”, delivery ketone bodies by means of a simple drink. Containing betahydroxybutyrate and medium chain triglycerides (which help with fat oxidation) with ZERO SUGAR, this formula is a game changer. Dr. Dominic D’Agostino at the University of South Florida has given many presentations at workshops and conferences about how importance the presence of ketone bodies are in minimizing (and frequently eliminating) diabetes, Alzheimer’s, epilepsy and cancer.

Even on the smaller scale, KETO//OS “contains a specifically engineered ratio of proprietary ketone mineral salts that provide a high-energy fuel compound without having to incorporate an energy-restricted diet”. This means that your neighbors, your classmates, your parents, your best friend’s cousin, and your significant other are ALL able to benefit from using such an incredible source of exogenous ketone bodies. If you are ready to make that change in YOUR life, or the life of a loved one, visit the following site to get more information on the opportunities that lie ahead.

Joyously,

Coral Jinright

  • cj1005.pruvitnow.com
  • Poff, A.m., C. Ari, P. Arnold, T.n. Seyfried, and D.p. D’agostino. “Ketone Supplementation Decreases Tumor Cell Viability and Prolongs Survival of Mice with Metastatic Cancer.” International Journal of Cancer Int. J. Cancer 135.7 (2014): 1711-720. Web.