Posted in Ketogenic Life, Of Heart and Mind

PTSD vs. TBI Using SPECT Scans

Because CT and MRI scans are unable to detect with sensitivity and specificity what a SPECT scan can when diagnosing mild TBI and PTSD, a group of researchers (Daniel G. Amen ,Cyrus A. Raji , Kristen Willeumier , Derek Taylor , Robert Tarzwell , Andrew Newberg , and Theodore A. Henderson) chose to use SPECT scans to see if they could find a true difference between the brain of those with TBI and PTSD. SPECT scans provide the clinical utility of the “delineation of the neural circuitry underlying PTSD ” and the improved detection of TBI. The SPECT scans in this study contain populations of those with PTSD, TBI, co-morbidities as well as those unaffected by either. The following is a collection of the statistics of those with PTSD and TBI in both military and civilian populations in the United States.

Military:

  • DoD reported 307,283 diagnosed cases of TBI from 2000–2014.
  • Congressional Research Service reporting 103,792 diagnosed cases of PTSD from 2000–2012.
  • Over 400,000 military personnel and veterans have been diagnosed with PTSD or TBI since 2001 [17, 18], and many have been diagnosed with both. The overlap of these two populations has been estimated at 33% [34, 35] to 42% [39]. among veterans. Those who have experienced a blast-related TBI have more than double the risk of developing PTSD.

Civilian:

  • About 7.7 million in the US population suffer from PTSD.
  • TBI is also quite prevalent, with 2.5 million annual visits to emergency rooms for suspected TBI.
  • 49% of those with TBI are likely to be diagnosed with a psychiatric illness the following year.

Although the majority of TBI symptoms can resolve over time, a significant proportion of cases develop a persistent post-concussive syndrome (PCS). Long-term consequences of seemingly trivial head injuries may be significant. TBI scans found these areas of the brain to be of particular interest (orbitofrontal cortex, temporal poles, and anterior cingulum) while PTSD scans found these more interesting (amygdala [9], corpus callosum [10], insula [11], anterior cingulum [1214] and hippocampus [15, 16]). A recent meta-analysis showed that PTSD patients had significant activation in midline areas implicated in self-referential processing and autobiographical memory.

The treatments for PTSD and TBI/PCS are different. Therefore, by reliably separating them and accurately identifying cases in which both are present, the use of the SPECT scan emerges as a genuine diagnostic need. All PTSD-identifying regions were hyperactive on SPECT when compared across all groups, and the TBI-identifying regions were correspondingly hypoactive.

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Perfusion is defined by Merriam-Webster Medical Dictionary as “the pumping of a fluid through an organ or tissue”; in this instance, through the brain. When you look at the scans above, you can truly see the differences in perfusion across the four groups receiving SPECT scans. A healthy control shows normal higher perfusion to the cerebellum. The PTSD subject shows increased perfusion in the brain—particularly in the frontal lobes. The TBI subject shows decreased perfusion throughout by comparison. The subject with both PTSD and TBI shows perfusion that is lower than the person with PTSD but higher than the subject with TBI. These results suggest that TBI is associated with hypoperfusion while PTSD is associated with regional hyperperfusion, which both provide  important insights in regards to the pathophysiological differences between the disorders.

Many research studies have found the positive benefits that pure therapeutic ketones have on the perfusion across the brain, along with the neural communication across its lobes. If you or anyone you know are interested in getting a SPECT scan of your brain, visit one of the Amen Clinics across the nation! My goal is to get this information into the hands of those affected by TBI and PTSD, and hopefully this will aid in doing so!

With warm regards,

Coral A.J. Gibson

 

Posted in Ketogenic Life

Ketosis vs. Ketoacidosis

Frequently, I encounter medical professionals who have a negative connotation associated with the words “ketosis” and “ketones”. Why is that?

In school, medical students are taught that ketones are present in the body when a diabetic patient is succumbing to kidney failure because of the excess presence of ketones in the bloodstream. With that knowledge, it seemed unfathomable how ketones could possibly be beneficial or even therapeutic. However, there’s something missing here. The aforementioned situation is a state called ketoacidosis.

In this state of ketoacidosis, blood ketone levels are above 10mmol AND blood glucose levels are high. The body becomes unable to utilize glucose for fuel; that glucose stays in the body and fat is broken down to create ketones for fuel. Then, “without insulin to control the amount of ketones produced during this process, an excessive amount is produced.” This is a vicious cycle. On the flip side, in a state of ketosis, optimal blood ketone levels are between 0.5 and 3 mmol AND blood glucose levels are stabilized.

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Can you see the difference there?

In a state of ketoacidosis, the body struggles to use both glucose and ketones as a fuel source, and is soon affected by this toxic state. Insulin and glucagon are unstable.

In a state of ketosis, the body is utilizing ketones as the primary fuel source with assistance from glucose as need be. The use of dual fuel is the ideal metabolism for the majority of the population. Reference my other articles to see why this concept of dual fuel is so important in your health and longevity.

To a better fuel source,

Coral A.J. Gibson

 

Posted in Ketogenic Life

Exogenous vs. Endogenous Ketones

The empirical research and powerful testimonials concerning ketosis are of abundance.

You might have had this question run across your mind, like many people looking for health optimization: what is the difference between taking exogenous ketones and following a ketogenic diet?

Either way, the body will benefit. Let’s talk about this difference.

Simply put, “exogenous” refers to something that is sourced from outside of the body. All supplements are therefore considered exogenous because they are ingested rather than created by the body. “Endogenous” refers to something created within the body.

Is that simplified enough? I hope so.

Now the question becomes what are the implications of that exogenous vs. endogenous? Are there any specific differences between taking exogenous ketones and producing endogenous ketones? This video from Michael Rutherford clearly explains the difference; don’t let it be too complicated.

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Alchemy Athletics provides this incredible insight to the community. Endogenous “ketosis can be unsustainable in the long-term considering that just a small amount of carbohydrates or excess protein can kick you out of ketosis.” This is very true. And this is why exogenous ketone use can be so handy in long-term health and wellness. Learn more about the benefits of exogenous ketone supplementation in Alchemy Athletics’ Ketones 101 and read through the resources listed at the bottom of the article!

Onward and Upward,

Coral A.J. Gibson

Posted in Ketogenic Life

Break Through KETO Weight-Loss Plateaus

I’ve had a few people this month ask me how they can break through the weight loss plateau they are experiencing after months of being on a ketogenic diet and taking exogenous ketones. First, props to them for keeping up with the ketogenic lifestyle for months! Many people can’t find the desire or discipline to stick with it for more than a couple weeks; so way to go! Second, it is PERFECTLY normal to experience a plateau in your weight loss goal; the trick is to not let it defeat you. If you’ve been at this plateau for more than three weeks, today’s message will help you learn how to break through it!

In this interview on Cut the Killer Carbs, Dr. Justin Anderson discusses a few of the challenges his clients are experiencing during their metabolic coaching programs. He says about 10% of metabolic coaching clients experience these plateaus.  The Whoosh Effect is the collection of instances when your body can go a certain period of time with no movement in the weight, then all of a sudden drop a couple pounds and go right back to no movement. Here a few tricks to break your plateau:

  1. Count your carbs, religiously, for three days. After awhile, you become lax on your carb consumption. Put yourself back in check.
  2. Take a look at current medications, as some are associated with weight gain.
  3. Check your axial temperature in the morning to see if you have inadequate thyroid function.
  4. Take omega 3 fatty acids!
  5. Consider a light exercise regimen.
  6. Try two weeks of dairy to see if your body is sensitive to it.
  7. If you’re on current thyroid meds, switch from generic to name brand for more bioavailability.
  8. Watch out for farm-raised fish; get wild caught only.
  9. Remove diet sodas and artificial sweeteners.
  10. Don’t let your “cheats” go too far.
  11. Utilize intermittent fasting.

Here is another great resource for even more tips on how to break through your plateau, including eating too much or too little!

My personal recommendation for my clients is to change your daily routine. If you’ve been following the same regimen for more than six months, give your body something new to work with. Do high intensity movement for 5 minutes before you start your day. Use intermittent fasting at a different 8 hour time slot in the day. Up your exogenous ketone consumption a little! If you’ve been using 1/2 packet twice a day for months, try using 1/2 packet three times a day for a bit. If you haven’t implement the use of exogenous ketones in your weight loss journey, start now and see if that brings your cellular regeneration to a new level!

I hope this will help you get where you’re looking to go. As always, if these tips aren’t helping you break through, consult a medical professional to address your body’s needs.

Best of Luck,

Coral Jinright-Gibson

Posted in Ketogenic Life

Gut Health and Ketosis

It’s no question if gut health should be at the top of your list of health goals. Yet, surprisingly, many people will focus much more on cosmetic and aesthetic “health” and completely bypass what’s going on inside their bodies. The microbiome in the gut is highly influenced by the types of food we put into it. Primarily, sugar and “empty” carbs are the ones in question here. You can imagine that, if sugar is bad for the brain, it’s not so good for the intestines either! We will now explore this with a view interviews!

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In this interview, Eric Westman MD talks about how the ketogenic diet affects the health of our digestion and the trillions of microbes inside our guts. Contrary ideas are also brought to the table in an attempt to truly understand what takes place when sugar and empty carbs are removed from our diet.

 

In this interview, David Perlmutter MD, a board certified neurologist, discusses how the removal of grains and the inclusion of a ketogenic diet could aid in protecting our brains for life. The power of gut microbes is incredible, but fat got the blame for its decline in recent decades, contrary to practices by humans over thousands of years.

Both of these interviews are full of knowledge, as well as links to other books and research articles to expand what you know about the connection between the brain and the gut microbiome and just how helpful ketosis is in maintaining the health of both.

Health and happiness,

Coral Jinright

 

Posted in Ketogenic Life

Insulin Stability and Ketones

Alright, it’s time to get serious about this epidemic. Everyday, people talk about their health status with friends, family members, as well as health professionals. Obesity and diabetes are frequent discussion topics in many countries of the world, but the United States blows statistics out of the water.

Check this out! The Center of Disease Control and Prevention (CDC) collected infographic data comparing the prevalence of type-2 diabetes in adults over the age of 18 in each state annually from 1994 to 2014. These statistics are astounding and disgusting!

In 1994, South Carolina was the only state to have a prevalence over 6.0%. Let’s jump forward to 1999. Mississippi  becomes the only state to have a prevalence over 7.5%. At the same time, the number of states with less than 4.5% prevalence decreased from 25 to 8; 17 of those states climbed their way up to the next percentage bracket. The most appalling of all is 2014. The lowest prevalence is 6.0%, and more than half of the United States is over 9.0% type-2 diabetic!

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CAN YOU BELIEVE THIS?!?! I don’t think people truly understand the significance of this diagnosis when it is given by a physician. Most go on living their “normal” life, but utilize insulin in a medication as a means to moderate their blood sugar levels. What they don’t understand is that “logically, insulin does not help reverse the disease, but actually worsens it.” Insulin resistance makes the human body gain weight, and gaining weight definitely does not improve type-2 diabetes. “We’ve been prescribing drugs for a dietary disease. No wonder it doesn’t work.” I love this statement. So let’s dig a little deeper and see what actually needs to take place to reverse this monstrous disease overtaking our people.

Insulin is a hormone produced when we eat, which allows glucose into the cells. Once insulin is unable to do so, glucose just piles up outside the cell in the blood, creating what’s called insulin resistance. The cells are already over-filled with glucose, so now they resist the glucose because it is completely at capacity. This insulin resistance (present in type-2 diabetes) can only be reversed with the extreme moderation of sugar in the diet!

Now that you understand the cause of type-2 diabetes, let’s look at the reversal (or treatment) of it! First of all, don’t put more sugar in your body! Adapting to a low carb, high fat diet is highly recommended for an individual with type-2 diabetes. Cleansing the liver of excess sugar and providing a stability in blood glucose levels will help put the body in ketosis and burn off fat (adipose tissue) as fuel, lower your weight and combat type-2 diabetes! Integrating intermittent fasting and an exercise program will also help to lower blood glucose levels! To learn more about what it means to follow a ketogenic diet, read What Do I Eat to Flourish? While maintaining a ketogenic diet can be a challenge, and huge shift from your previous eating habits, exogenous ketones can be consumed to help expedite this process by moderating blood glucose levels and increasing blood ketone levels. To understand how exogenous ketones help the body become insulin sensitive rather than resistance, check out Can’t Commit to the Keto Diet Yet?

I hope this information will help you, a loved one, a friend, co-worker or even your next door neighbor understand more the effects sugar have on your body. Remember: you only have one body to live in, so take care of it every single day. Thank you to Dr. Andra Campitelli for sharing the link on Facebook to Jason Fung’s “How to Reverse Type 2 Diabetes” and inspiring this post.

Lovingly,

Coral Jinright

 

Resources

Maps of Trends in Diagnosed Diabetes: https://www.cdc.gov/diabetes/statistics/slides/maps_diabetes_trends.pdf

How to Reverse Type 2 Diabetes:  https://intensivedietarymanagement.com/reverse-type-2-diabetes-the-quick-start-guide/

Posted in Ketogenic Life

Ketones and Sleep

Thank you for your patience! I slacked off on my posts the past couple of weeks. But I’m back and ready to rock and roll!! Today’s topic is SLEEP. I’ve gotten so many clients who have raved about how much sleep has improved upon implementing their exogenous ketones on a daily basis. Rather than taking hours to fall asleep or waking up multiple times a night, they begin experiencing SLEEP!! And if you know anything about sleep, it is the most powerful form of mental and physical recovery and stress relief.

As avid exercisers, the exogenous ketones help repair inflammation in both body and brain tissues more rapidly and effectively!! How incredible is that?!

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If you don’t get sufficient sleep! (General terms)

Sleep is entirely a brain thing. Neuroscience can dig into the concept of sleep in more detail than you could ever imagine. Conditions such as epilepsy, sleep apnea, narcolepsy, TBI, concussions (among others) are 100% controlled by the brain. In providing more fuel to the brain to reduce inflammation and provide circulation of blood and nutrients through the use of exogenous ketones, your brain may be able to heal itself. Once again, you will be able to thoroughly enjoy the beauty sleep we all require. Giving the brain this super jet fuel (as many people have come to call it!) also makes sure the brain does not get depleted of vital nutrients, which may restrict certain parts of the brain unannounced.

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If you don’t get sufficient sleep! (Science jargon)

For today’s post, I would like to share with you some fantastic podcasts and videos that you are able to listen to during a busy day. You can plug it in and listen while you go on a trail walk, or play it on your computer speakers while you clean up the house. Whatever you may be doing, take some time to listen to the abundance of knowledge the following experts bring to the conversation.

This first one is from Tim Ferriss’ podcast as he talks with Dr. Dominic D’Agostino (whom you’ve heard about plenty on my site) and Dr. Peter Attia on the topic of exogenous ketones and jet fuel! http://fourhourworkweek.com/2015/11/03/dominic-dagostino/

On this second site, Dr. D’Agostino’s blog site, he shares a TED Talk he presented discussing the use of the ketogenic diet for patients with epilepsy and cancer. http://ketonutrition.blogspot.com/2014/02/the-charlie-foundation-for-ketogenic.html?view=sidebar

Wishing you a good night’s rest,

Coral J.

cj1005.pruvitnow.com

Posted in Ketogenic Life

What Do I Eat to Flourish?

So you’ve read through all of the posts about the ketogenic diet and its application in helping to resolve different health conditions. Whether you think you just need a little energy and productivity boost throughout or work or school day, or if you are ready to lower your triglyceride levels, stop taking your medicine for high blood pressure and lose 15 pounds, I’ve got you covered. Pruvit’s KETO//OS is an incredible addition to your daily routine to help you achieve your mental and physical goals you have set for yourself. This can be added to your current diet as you continue to adapt to become a fat-burning furnace, but is also the perfect complement to a ketogenic diet.

By implementing the ketogenic diet, we will transform your body into the optimal fat-burning machine it was meant to be. Though the Standard American Diet has made us believe oatmeal with bananas and orange juice is a perfect breakfast, the Low Carb High Fat Diet (LCHF) makes your body burn FAT and form KETONES right from the get-go.

The first step of this ketogenic diet is to limit your carb intake. Remove your pantry of the pastas, rice, oatmeal, bread, cereal, donuts, beans and set your eye on fats. Granted, ONE cheat meal a week is acceptable, but really try to stay motivated on your goal and stick with only that one cheat meal. Keep the fats high, proteins moderate, and carbs less than 20 g. If you are an athlete, try to do less than 50 g, but make the majority of your carbs immediately post workout. The second step is to work in intermittent fasting. Try to consume your exogenous ketones from Pruvit first thing when you wake up, or your coffee with some coconut oil and heavy whipping cream. This will feed your body some fat to get the oven burning. Now LISTEN to your body, and do not eat again until you are actually HUNGRY. That does not mean “wait until you smell your co-worker’s lunch” to go eat.

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The problem with our society right now is that we always eat when we feel we are supposed to, not when our bodies NEED to. Try to wait and eat your first meal of the day about 5 hours after you wake up (or whenever you’re actually hungry). Keep the fat content high and protein moderate. Doing this will help you tune into the chemical communication between your brain and your stomach. If you’re anything like me, you’ve struggled to not eat half the peanut butter jar the second you open it to mix it up before storing it. Sometimes scents will DRAG you into consuming food, but RESIST the temptation. During your first two week so of the LCHF Diet, be patient with yourself. As your body goes through the keto-adaptation phase, you might feel a little sluggish, but push through because your body is about to make itself an incredible fat-burning machine. After you’ve become keto-adapted, the world is at your fingertips, and your body will start to reap all the benefits! If you are a pescatarian or vegetarian, please ensure you look to other sources, such as eggs and cheese, for your protein. Focus on making 80% of your intake FATS and keep your protein moderate (between 10 and 15%) and carbs minimal (5-10%).

Starting a new nutrition lifestyle is always a challenge. To help you make better decisions at the grocery store, I’ve compiled a grocery list made by Jimmy Moore in his book “KETO Clarity” written with Dr. Eric Westman.

Download and print your ketogenic grocery list here: KetogenicDietGroceryList

Keep posted for a more in-depth analysis of your macronutrient (fat, carb, protein) ratios in the coming week. Like always, if you have any questions or concerns, please comment below or contact me via Facebook.

Sincerely,

Coral J.

Posted in Ketogenic Life

Polycystic Ovary Syndrome (PCOS) and the Ketogenic Diet Intervention

A good friend and co-worker of mine and I have been recently discussing her struggle with PCOS and the research I have collected to show the positive effects being in ketosis has on the human body for those women battling PCOS.  In light of our conversations, I found this would be a great opportunity to share this with other women who could benefit from having this knowledge!

Polycystic Ovary Syndrome (PCOS) is often associated with symptoms of excess testosterone: irregular or absent menses, excessive body hair,  and infertility. PCOS is also associated with medical abnormalities such as central obesity, insulin resistance, hyperinsulinemia, type 2 diabetes mellitus, and dyslipidemia.

PCOS Awareness Infographic
PCOS Awareness Infographic (PRNewsFoto/PCOS Challenge, Inc.)

A pilot study conducted in 2005 by John C MavropoulosWilliam S YancyJuanita Hepburn, and  Eric C Westman instructed 5 females who passed a screening test based on diagnosis of having PCOS, chronic anovulation (missing or irregular menses) and a BMI greater than 27 kg/m2. In summary, in this pilot study, LCKD was followed consisting of the following parameters:

  1. fewer than 20 grams of carbohydrate per day (as tolerated throughout the 6-month study period)
  2. unlimited consumption of animal foods (meat, chicken, turkey, other fowl, fish, shellfish)
  3. prepared and fresh cheeses (up to 4 and 2 ounces per day, respectively)
  4. unlimited eggs
  5. salad vegetables (2 cupfuls per day)
  6. low carbohydrate vegetables (1 cupful per day)
  7. strongly encouraged to drink at least six 8-ounce glasses of permitted fluids per day
  8. encouraged to take one multivitamin per day
  9. encouraged to exercise at least three times per week on their own, although this was not mandatory
  10. discouraged to drink caffeine and alcohol

This pilot study showed that adherence to a LCKD led to improvement in body weight, percent free testosterone, LH/FSH ratio (associated with fertility), fasting serum insulin, and other symptoms in women diagnosed with PCOS over a six-month period.

In “KETO Clarity” by Jimmy Moore and Eric Westman, MD, the effects of a ketogenic diet on PCOS is again highly acknowledged. Referring to the same study referenced above, women had an average weight loss of 12% (i.e. decrease from 180 lbs to 159 lbs!) In fact, it was also reported that 2 of the 5 women actually became pregnant DURING the study despite previous infertility issues. ASTOUNDING!! In conjunction with a low-carb, high fat ketogenic diet (LCKD) and regular exercise, Pruvit’s exogenous ketones as part of the Ketone Operating System put the body in ketosis in under 59 minutes to reap the benefits even quicker (see link below)!

If you are also interested in listening to stories from other women with PCOS and their success with the ketogenic diet, tune into KetoKarma’s Youtube video at https://www.youtube.com/watch?v=_3yzxCrpGXY.

Resources:

Posted in Ketogenic Life

Can’t Commit to the Keto Diet Yet?

Do you have a spouse that’s skeptical about you taking their spaghetti and garlic bread out of their weekly meal plan? A child that is in a routine of cereal for breakfast and a PB&J sandwich for lunch? A friend that laughs when you even mention the possibility that carbs can be removed from your diet and have BENEFIT? I’m sure that everyone has some doubt that this “ketogenic” phase will come and go like every other diet fad out there. Even with that skepticism, there’s still a first step that can be taken to increase the function of your body, even if you are currently consuming carbs. Putting your body into a state of ketosis is a MIRACULOUS thing.

A study conducted in 2014 discusses that “ketone metabolism by healthy tissue would likely mitigate some of the adverse side effects of standard of care as ketones have been shown to protect against oxidative stress” (Poff, Ari, Arnold, Seyfried and D’Agostino). This means to say that even though you may not limit your consumption of carbohydrates enough to keep your body in a state of ketosis, the consumption of supplemental exogenous ketones can help keep your body in such a state and still reap the benefits of the ketogenic diet. Triglyceride levels decrease, HDL (good cholesterol) levels increase, insulin resistance decreases and blood pressure decreases. For all of these things to take place without a single medication is ASTOUNDING!

Betahydroxybutyrate is a ketone ester naturally occurring in the body, but is not utilized well in a high-carb low-fat diet. Supplementation of this ketone ester has shown to be “a feasible and efficacious cancer therapy” for mice, and is in the process of being more thoroughly investigated for cancer treatment for humans (Poff et al., 2014). If this ketone ester can rid the body of CANCER, it has a lot more to offer than any other supplement out there. So if your spouse, child, or friend wants to optimize the function of their body, there’s no other way to go. This is it, ladies and gentlemen!

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Pruvit’s KETO//OS is the “first of its kind”, delivery ketone bodies by means of a simple drink. Containing betahydroxybutyrate and medium chain triglycerides (which help with fat oxidation) with ZERO SUGAR, this formula is a game changer. Dr. Dominic D’Agostino at the University of South Florida has given many presentations at workshops and conferences about how importance the presence of ketone bodies are in minimizing (and frequently eliminating) diabetes, Alzheimer’s, epilepsy and cancer.

Even on the smaller scale, KETO//OS “contains a specifically engineered ratio of proprietary ketone mineral salts that provide a high-energy fuel compound without having to incorporate an energy-restricted diet”. This means that your neighbors, your classmates, your parents, your best friend’s cousin, and your significant other are ALL able to benefit from using such an incredible source of exogenous ketone bodies. If you are ready to make that change in YOUR life, or the life of a loved one, visit the following site to get more information on the opportunities that lie ahead.

Joyously,

Coral Jinright

  • cj1005.pruvitnow.com
  • Poff, A.m., C. Ari, P. Arnold, T.n. Seyfried, and D.p. D’agostino. “Ketone Supplementation Decreases Tumor Cell Viability and Prolongs Survival of Mice with Metastatic Cancer.” International Journal of Cancer Int. J. Cancer 135.7 (2014): 1711-720. Web.